Since Update 1 (build 6525) of Acronis True Image 2015 the software supports smart exclusions in Entire PC backup to Acronis Cloud: it is now possible to exclude files that are already protected by other applications (e.g. Dropbox, iTunes media library and others). The option is available if the data protected by other applications exceeds 250MB.
- Create a backup task for Entire PC to Acronis Cloud.
- Click:
Excluded: Edit on PC Optimize backup on Mac 
Acronis True Image 2015: Back up faster on PC Acronis True Image 2015 for Mac: Optimize backup on Mac - Select data you want to exclude:
